The St. Louis Cardinals (14-12) face the Pittsburgh Pirates (16-11) on Monday, April 27, 2026 at 6:40 PM ET on Regional Sports Network. Dustin May takes the mound against TBD. Our model gives Pittsburgh Pirates a 60% edge.
Quick Facts
| Matchup | St. Louis Cardinals at Pittsburgh Pirates |
| Date | Monday, April 27, 2026 |
| First Pitch | 6:40 PM ET |
| Venue | PNC Park |
| TV | Check local listings / MLB.TV |
| Streaming | MLB.TV |
| Probable Pitchers | Dustin May vs TBD |
Where to Watch STL vs PIT
The St. Louis Cardinals visit the Pittsburgh Pirates on Monday, April 27, 2026 with first pitch at 6:40 PM ET. The game will air on Regional Sports Network and can be streamed on MLB.TV.
Pitching Matchup
Dustin May takes the mound for the St. Louis Cardinals against TBD for the Pittsburgh Pirates.
Matchup Analysis
The St. Louis Cardinals (14-12) have a 40% win probability in our model.
The Pittsburgh Pirates (16-11) are given a 60% chance with home field advantage.
This is an NL Central divisional matchup with direct implications for the division standings.
Head-to-Head
Season Series
Tied 1-1Recent Form
St. Louis Cardinals — Last 5 Games
1-4 · Streak: L3Pittsburgh Pirates — Last 5 Games
3-2 · Streak: W2See live scores: MLB Scores