The San Diego Padres (20-14) face the San Francisco Giants (14-21) on Wednesday, May 06, 2026 at 3:45 PM ET on Regional Sports Network. Matt Waldron takes the mound against Adrian Houser. Our model gives San Diego Padres a 68% edge.
Quick Facts
| Matchup | San Diego Padres at San Francisco Giants |
| Date | Wednesday, May 06, 2026 |
| First Pitch | 3:45 PM ET |
| Venue | Oracle Park |
| TV | Check local listings / MLB.TV |
| Streaming | MLB.TV |
| Probable Pitchers | Matt Waldron vs Adrian Houser |
Where to Watch SD vs SF
The San Diego Padres visit the San Francisco Giants on Wednesday, May 06, 2026 with first pitch at 3:45 PM ET. The game will air on Regional Sports Network and can be streamed on MLB.TV.
Pitching Matchup
Matt Waldron takes the mound for the San Diego Padres against Adrian Houser for the San Francisco Giants.
Matchup Analysis
The San Diego Padres (20-14) have a 68% win probability in our model.
The San Francisco Giants (14-21) are given a 32% chance with home field advantage.
This is an NL West divisional matchup with direct implications for the division standings.
Head-to-Head
Season Series
SF leads 4-2Recent Form
San Diego Padres — Last 5 Games
1-4 · Streak: L1San Francisco Giants — Last 5 Games
1-4 · Streak: W1See live scores: MLB Scores