The Chicago White Sox (8-14) face the Arizona Diamondbacks (13-9) on Tuesday, April 21, 2026 at 9:40 PM ET on Regional Sports Network. Sean Burke takes the mound against Merrill Kelly. Our model gives Arizona Diamondbacks a 77% edge.
Quick Facts
| Matchup | Chicago White Sox at Arizona Diamondbacks |
| Date | Tuesday, April 21, 2026 |
| First Pitch | 9:40 PM ET |
| Venue | Chase Field |
| TV | Check local listings / MLB.TV |
| Streaming | MLB.TV |
| Probable Pitchers | Sean Burke vs Merrill Kelly |
Where to Watch CWS vs ARI
The Chicago White Sox visit the Arizona Diamondbacks on Tuesday, April 21, 2026 with first pitch at 9:40 PM ET. The game will air on Regional Sports Network and can be streamed on MLB.TV.
Pitching Matchup
Sean Burke takes the mound for the Chicago White Sox against Merrill Kelly for the Arizona Diamondbacks.
Matchup Analysis
The Chicago White Sox (8-14) have a 23% win probability in our model.
The Arizona Diamondbacks (13-9) are given a 77% chance with home field advantage.
Head-to-Head
Season Series
CWS leads 2-0W 6-0 @ ARI (Mar 06)W 4-2 vs ARI (Mar 20)
Recent Form
Chicago White Sox — Last 5 Games
2-3 · Streak: W1W 7-4 @ AthleticsApr 19
L 6-7 @ AthleticsApr 18
W 9-2 @ AthleticsApr 18
L 3-5 vs Tampa Bay RaysApr 16
L 3-8 vs Tampa Bay RaysApr 15
Arizona Diamondbacks — Last 5 Games
4-1 · Streak: L1L 4-10 vs Toronto Blue JaysApr 19
W 6-2 vs Toronto Blue JaysApr 19
W 6-3 vs Toronto Blue JaysApr 18
W 8-5 @ Baltimore OriolesApr 15
W 4-3 @ Baltimore OriolesApr 14
See live scores: MLB Scores