The Cleveland Guardians (10-8) face the St. Louis Cardinals (9-8) on Wednesday, April 15, 2026 at 1:15 PM ET on Regional Sports Network. Slade Cecconi takes the mound against Dustin May. Our model gives St. Louis Cardinals a 51% edge.
Quick Facts
| Matchup | Cleveland Guardians at St. Louis Cardinals |
| Date | Wednesday, April 15, 2026 |
| First Pitch | 1:15 PM ET |
| Venue | Busch Stadium |
| TV | Check local listings / MLB.TV |
| Streaming | MLB.TV |
| Probable Pitchers | Slade Cecconi vs Dustin May |
Where to Watch CLE vs STL
The Cleveland Guardians visit the St. Louis Cardinals on Wednesday, April 15, 2026 with first pitch at 1:15 PM ET. The game will air on Regional Sports Network and can be streamed on MLB.TV.
Pitching Matchup
Slade Cecconi takes the mound for the Cleveland Guardians against Dustin May for the St. Louis Cardinals.
Matchup Analysis
The Cleveland Guardians (10-8) have a 49% win probability in our model.
The St. Louis Cardinals (9-8) are given a 51% chance with home field advantage.
Head-to-Head
Season Series
Tied 1-1W 9-3 @ STL (Apr 13)L 5-6 @ STL (Apr 14)
Recent Form
Cleveland Guardians — Last 5 Games
2-3 · Streak: L1L 5-6 @ St. Louis CardinalsApr 14
W 9-3 @ St. Louis CardinalsApr 13
L 1-13 @ Atlanta BravesApr 12
W 6-0 @ Atlanta BravesApr 11
L 5-11 @ Atlanta BravesApr 10
St. Louis Cardinals — Last 5 Games
2-3 · Streak: W1W 6-5 vs Cleveland GuardiansApr 14
L 3-9 vs Cleveland GuardiansApr 13
L 3-9 vs Boston Red SoxApr 12
L 1-7 vs Boston Red SoxApr 11
W 3-2 vs Boston Red SoxApr 11
See live scores: MLB Scores