NFL teams have shifted away from drafting running backs early, with no first-round running backs in the previous year. The over/under for first-round running backs in 2025 is set at 2.5, with betting odds favoring under at -150 and over at +120 on DraftKings.
Boise State's Ashton Jeanty is a highly likely first-round pick, expected to go in the 6-10 range. North Carolina's Omarion Hampton follows as a safe bet for a first-round selection, heavily favored at -1400. Potential third running back options include TreVeyon Henderson or Quinshon Judkins from Ohio State, while long shots include Iowa's Kaleb Johnson and Arizona State's Cam Skattebo.
The league's perception of running back value may be evolving following Saquon Barkley's impact with the Eagles in winning the Super Bowl. This shift could potentially lead to three running backs being selected in the first round for the first time since Barkley's entry into the NFL.